Opaleye Management Inc.
CIK 1595855
Transactions on file
167
Open-market buys
108
Win rate (buys)
50%
105 scored
Avg % since filing (buys)
+14.7%
Tickers traded
Recent activity
| Filed | Txn date | Issuer | Roles | Code | Shares | Value | % since Filing | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-09-16 | 2026-09-16 | ACOG Alpha Cognition Inc. | 10% | Buy | 27,141 | $228.0K | +4.8% | open → |
| 2026-09-16 | 2026-09-16 | ACOG Alpha Cognition Inc. | 10% | Buy | 53,029 | $454.6K | +2.7% | open → |
| 2026-09-16 | 2026-09-15 | ACOG Alpha Cognition Inc. | 10% | Buy | 3,375 | $28.8K | +3.0% | open → |
| 2026-09-16 | 2026-09-14 | ACOG Alpha Cognition Inc. | 10% | Buy | 40,373 | $351.1K | +1.2% | open → |
| 2026-09-14 | 2026-09-11 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 1,493 | $98.5K | -3.8% | open → |
| 2026-09-14 | 2026-09-10 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 1,631 | $108.9K | -5.0% | open → |
| 2026-09-10 | 2026-09-09 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 5,836 | $12.2K | +6.7% | open → |
| 2026-09-10 | 2026-09-08 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 9,393 | $19.7K | +6.3% | open → |
| 2026-09-09 | 2026-09-09 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 3,097 | $212.8K | -7.7% | open → |
| 2026-09-09 | 2026-09-08 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 471 | $32.7K | -8.5% | open → |
| 2026-09-09 | 2026-09-08 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 3,390 | $233.0K | -7.7% | open → |
| 2026-09-09 | 2026-09-04 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 2,100 | $144.9K | -8.0% | open → |
| 2026-09-09 | 2026-09-04 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 918 | $63.8K | -8.7% | open → |
| 2026-09-03 | 2026-09-02 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 900 | $62.1K | -8.0% | open → |
| 2026-09-03 | 2026-09-01 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 783 | $54.4K | -8.7% | open → |
| 2026-08-31 | 2026-08-31 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 217 | $15.0K | -8.2% | open → |
| 2026-08-31 | 2026-08-31 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 5,000 | $341.2K | -7.0% | open → |
| 2026-08-31 | 2026-08-28 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 5,000 | $344.1K | -7.8% | open → |
| 2026-08-31 | 2026-08-28 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 20,113 | $1.38M | -7.3% | open → |
| 2026-08-31 | 2026-08-28 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 10,000 | $714.0K | -11.1% | open → |
| 2026-08-19 | 2026-08-14 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 11,608 | $24.2K | +6.9% | open → |
| 2026-08-14 | 2026-08-12 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 951 | $68.0K | -11.3% | open → |
| 2026-08-04 | 2026-08-03 | ACOG Alpha Cognition Inc. | 10% | Buy | 50,000 | $400.0K | +10.0% | open → |
| 2026-08-04 | 2026-07-31 | ACOG Alpha Cognition Inc. | 10% | Buy | 2,900 | $23.0K | +11.1% | open → |
| 2026-07-28 | 2026-07-24 | ACOG Alpha Cognition Inc. | 10% | Buy | 130 | $1.0K | +11.4% | open → |
| 2026-07-24 | 2026-07-23 | ACOG Alpha Cognition Inc. | 10% | Buy | 49,849 | $388.6K | +12.9% | open → |
| 2026-07-24 | 2026-07-22 | ACOG Alpha Cognition Inc. | 10% | Buy | 10,000 | $78.3K | +12.3% | open → |
| 2026-07-24 | 2026-07-22 | ACOG Alpha Cognition Inc. | 10% | Buy | 140,237 | $1.10M | +12.3% | open → |
| 2026-07-17 | 2026-07-14 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 13,315 | $499.9K | +46.3% | open → |
| 2026-07-17 | 2026-07-14 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 15,000 | $563.1K | +46.3% | open → |
| 2026-07-16 | 2026-07-14 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 13,315 | $499.9K | +46.3% | open → |
| 2026-07-16 | 2026-07-14 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 15,000 | $563.1K | +46.3% | open → |
| 2026-07-15 | 2026-07-14 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 920 | $67.6K | -13.6% | open → |
| 2026-07-15 | 2026-07-13 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 775 | $57.3K | -14.1% | open → |
| 2026-07-10 | 2026-07-10 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 229 | $16.9K | -14.2% | open → |
| 2026-07-10 | 2026-07-08 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 300 | $22.1K | -13.9% | open → |
| 2026-07-07 | 2026-07-07 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 6,685 | $256.5K | +43.1% | open → |
| 2026-07-07 | 2026-07-07 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 20,000 | $767.5K | +43.1% | open → |
| 2026-07-07 | 2026-07-06 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 10,000 | $380.0K | +44.6% | open → |
| 2026-07-07 | 2026-07-02 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 25,000 | $934.6K | +46.9% | open → |
| 2026-07-07 | 2026-07-02 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 65,000 | $2.43M | +46.9% | open → |
| 2026-06-29 | 2026-06-26 | ACOG Alpha Cognition Inc. | 10% | Buy | 152,336 | $975.2K | +37.5% | open → |
| 2026-06-29 | 2026-06-25 | ACOG Alpha Cognition Inc. | 10% | Buy | 197 | $1.3K | +35.4% | open → |
| 2026-06-16 | 2026-06-15 | ACOG Alpha Cognition Inc. | 10% | Buy | 4,550 | $27.3K | +46.9% | open → |
| 2026-06-16 | 2026-06-12 | ACOG Alpha Cognition Inc. | 10% | Buy | 273 | $1.6K | +48.3% | open → |
| 2026-06-16 | 2026-06-11 | ACOG Alpha Cognition Inc. | 10% | Buy | 2,862 | $16.9K | +49.0% | open → |
| 2026-06-11 | 2026-06-10 | ACOG Alpha Cognition Inc. | 10% | Buy | 5,872 | $35.2K | +47.0% | open → |
| 2026-06-11 | 2026-06-09 | ACOG Alpha Cognition Inc. | 10% | Buy | 24,856 | $148.5K | +47.3% | open → |
| 2026-06-09 | 2026-06-05 | ACOG Alpha Cognition Inc. | 10% | Buy | 10,054 | $58.6K | +51.0% | open → |
| 2026-05-29 | 2026-05-29 | ACOG Alpha Cognition Inc. | 10% | Buy | 70,577 | $416.4K | +49.2% | open → |
| 2026-05-29 | 2026-05-28 | ACOG Alpha Cognition Inc. | 10% | Buy | 2,000 | $11.7K | +50.9% | open → |
| 2026-05-29 | 2026-05-27 | ACOG Alpha Cognition Inc. | 10% | Buy | 1,161 | $6.7K | +53.6% | open → |
| 2026-05-22 | 2026-05-20 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 1,563 | $100.7K | -1.5% | open → |
| 2026-05-22 | 2026-05-21 | ACOG Alpha Cognition Inc. | 10% | Buy | 15,945 | $90.9K | +54.4% | open → |
| 2026-05-22 | 2026-05-20 | ACOG Alpha Cognition Inc. | 10% | Buy | 8,431 | $49.7K | +49.4% | open → |
| 2026-05-19 | 2026-05-18 | ACOG Alpha Cognition Inc. | 10% | Buy | 17,395 | $99.0K | +54.6% | open → |
| 2026-05-19 | 2026-05-15 | ACOG Alpha Cognition Inc. | 10% | Buy | 16,648 | $97.0K | +51.1% | open → |
| 2026-05-14 | 2026-05-13 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 1,937 | $129.5K | -5.1% | open → |
| 2026-05-14 | 2026-05-12 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 1,500 | $102.0K | -6.7% | open → |
| 2026-04-21 | 2026-04-21 | SNWV SANUWAVE Health, Inc. | 10% | Sale | 202 | $4.1K | — | open → |
| 2026-04-21 | 2026-04-17 | SNWV SANUWAVE Health, Inc. | 10% | Sale | 5,000 | $102.3K | — | open → |
| 2026-04-21 | 2026-04-17 | SNWV SANUWAVE Health, Inc. | 10% | Sale | 11,267 | $230.5K | — | open → |
| 2025-01-02 | 2024-12-31 | CDXS CODEXIS, INC. | 10% | Buy | 10,000 | $46.6K | -51.9% | open → |
| 2025-01-02 | 2024-12-30 | CDXS CODEXIS, INC. | 10% | Buy | 35,000 | $164.5K | -52.3% | open → |
| 2025-01-24 | 2025-01-22 | HROW HARROW, INC. | 10% | Sale | 20,000 | $711.8K | -4.9% | open → |
| 2025-01-31 | 2025-01-30 | CDXS CODEXIS, INC. | 10% | Buy | 20,000 | $89.8K | -50.1% | open → |
| 2025-01-31 | 2025-01-31 | CDXS CODEXIS, INC. | 10% | Buy | 45,000 | $193.1K | -47.8% | open → |
| 2025-02-12 | 2025-02-11 | CDXS CODEXIS, INC. | 10% | Buy | 12,500 | $51.4K | -45.5% | open → |
| 2025-02-12 | 2025-02-12 | CDXS CODEXIS, INC. | 10% | Buy | 15,000 | $60.0K | -44.0% | open → |
| 2025-02-12 | 2025-02-10 | CDXS CODEXIS, INC. | 10% | Buy | 22,500 | $94.0K | -46.4% | open → |
| 2025-03-04 | 2025-03-03 | CDXS CODEXIS, INC. | 10% | Buy | 47,351 | $133.1K | -20.3% | open → |
| 2025-03-04 | 2025-02-28 | CDXS CODEXIS, INC. | 10% | Buy | 147,649 | $441.5K | -25.1% | open → |
| 2025-03-04 | 2025-02-28 | HROW HARROW, INC. | 10% | Sale | 5,000 | $140.3K | +20.6% | open → |
| 2025-03-06 | 2025-03-04 | CDXS CODEXIS, INC. | 10% | Buy | 55,000 | $145.2K | -15.2% | open → |
| 2025-03-06 | 2025-03-05 | CDXS CODEXIS, INC. | 10% | Buy | 10,000 | $26.9K | -16.7% | open → |
| 2025-03-10 | 2025-03-06 | CDXS CODEXIS, INC. | 10% | Buy | 100,000 | $261.0K | -14.2% | open → |
| 2025-03-14 | 2025-03-13 | CDXS CODEXIS, INC. | 10% | Buy | 85,000 | $215.9K | -11.8% | open → |
| 2025-03-20 | 2025-03-18 | HROW HARROW, INC. | 10% | Sale | 5,000 | $148.2K | +14.2% | open → |
| 2025-03-24 | 2025-03-20 | CDXS CODEXIS, INC. | 10% | Buy | 7 | $17.98 | -11.8% | open → |
| 2025-03-24 | 2025-03-21 | CDXS CODEXIS, INC. | 10% | Buy | 92,923 | $236.0K | -11.8% | open → |
| 2025-03-26 | 2025-03-18 | HROW HARROW, INC. | 10% | Sale | 5,000 | $150.1K | +12.8% | open → |
| 2025-04-03 | 2025-04-02 | CDXS CODEXIS, INC. | 10% | Buy | 5,000 | $12.3K | -8.9% | open → |
| 2025-04-03 | 2025-04-03 | CDXS CODEXIS, INC. | 10% | Buy | 75,000 | $172.5K | -2.6% | open → |
| 2025-04-03 | 2025-04-01 | CDXS CODEXIS, INC. | 10% | Buy | 35,000 | $86.8K | -9.7% | open → |
| 2025-04-09 | 2025-04-08 | CDXS CODEXIS, INC. | 10% | Buy | 100,000 | $198.0K | +13.1% | open → |
| 2025-04-17 | 2025-04-17 | CDXS CODEXIS, INC. | 10% | Buy | 45,000 | $94.0K | +7.2% | open → |
| 2025-04-17 | 2025-04-16 | CDXS CODEXIS, INC. | 10% | Buy | 70,000 | $149.1K | +5.2% | open → |
| 2025-04-17 | 2025-04-15 | CDXS CODEXIS, INC. | 10% | Buy | 25,000 | $55.8K | +0.4% | open → |
| 2025-04-29 | 2025-04-25 | CDXS CODEXIS, INC. | 10% | Buy | 25,000 | $56.0K | +0.0% | open → |
| 2025-04-30 | 2025-04-29 | SNWV SANUWAVE Health, Inc. | 10% | Buy | 2,998 | $76.4K | — | open → |
| 2025-04-30 | 2025-04-29 | SNWV SANUWAVE Health, Inc. | 10% | Buy | 5,000 | $127.4K | — | open → |
| 2025-05-02 | 2025-04-30 | CDXS CODEXIS, INC. | 10% | Buy | 25,000 | $57.8K | -3.0% | open → |
| 2025-05-02 | 2025-05-01 | CDXS CODEXIS, INC. | 10% | Buy | 20,000 | $46.4K | -3.4% | open → |
| 2025-05-14 | 2025-03-24 | HROW HARROW, INC. | 10% | Sale | 5,000 | $150.1K | +12.8% | open → |
| 2025-05-14 | 2025-03-18 | HROW HARROW, INC. | 10% | Sale | 5,000 | $148.2K | +14.2% | open → |
| 2025-05-14 | 2025-05-13 | HROW HARROW, INC. | 10% | Sale | 5,000 | $132.9K | +27.3% | open → |
| 2025-05-14 | 2025-05-12 | HROW HARROW, INC. | 10% | Sale | 10,000 | $259.0K | +30.7% | open → |
| 2025-05-28 | 2025-05-23 | CDXS CODEXIS, INC. | 10% | Buy | 2,320,000 | $5.48M | -5.1% | open → |
| 2025-05-28 | 2025-05-28 | CDXS CODEXIS, INC. | 10% | Buy | 5,000 | $11.8K | -5.1% | open → |
| 2025-06-05 | 2025-06-03 | HROW HARROW, INC. | 10% | Sale | 3,000 | $90.1K | +12.6% | open → |
