Opaleye Management Inc.
CIK 1595855
Transactions on file
194
Open-market buys
135
Win rate (buys)
46%
132 scored
Avg % since filing (buys)
+1.0%
Tickers traded
Recent activity
| Filed | Txn date | Issuer | Roles | Code | Shares | Value | % since Filing | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-11-06 | 2026-11-05 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 3,087 | $5.5K | +5.1% | open → |
| 2026-11-06 | 2026-11-04 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 5,027 | $9.1K | +3.5% | open → |
| 2026-11-06 | 2026-11-03 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 10,328 | $18.5K | +4.2% | open → |
| 2026-10-26 | 2026-10-26 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 66,411 | $117.4K | +5.5% | open → |
| 2026-10-26 | 2026-10-22 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 21,390 | $41.2K | -3.2% | open → |
| 2026-10-26 | 2026-10-23 | ACOG Alpha Cognition Inc. | 10% | Buy | 14,973 | $123.3K | +6.0% | open → |
| 2026-10-26 | 2026-10-22 | ACOG Alpha Cognition Inc. | 10% | Buy | 17,117 | $142.5K | +4.8% | open → |
| 2026-10-21 | 2026-10-19 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 4,256 | $8.0K | -0.8% | open → |
| 2026-10-19 | 2026-10-16 | ACOG Alpha Cognition Inc. | 10% | Buy | 14,283 | $117.6K | +6.0% | open → |
| 2026-10-19 | 2026-10-15 | ACOG Alpha Cognition Inc. | 10% | Buy | 22,657 | $191.0K | +3.6% | open → |
| 2026-10-17 | 2026-10-16 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 36,347 | $68.8K | -1.4% | open → |
| 2026-10-17 | 2026-10-15 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 23,485 | $45.7K | -4.1% | open → |
| 2026-10-17 | 2026-10-14 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 11,233 | $21.7K | -3.6% | open → |
| 2026-10-13 | 2026-10-12 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 7,215 | $14.6K | -7.7% | open → |
| 2026-10-13 | 2026-10-09 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 5,340 | $10.9K | -8.8% | open → |
| 2026-10-13 | 2026-10-08 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 2,077 | $4.2K | -7.6% | open → |
| 2026-10-05 | 2026-10-05 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 1,694 | $3.5K | -9.5% | open → |
| 2026-10-05 | 2026-10-02 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 20,000 | $41.4K | -9.8% | open → |
| 2026-10-05 | 2026-10-01 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 38,796 | $79.0K | -8.4% | open → |
| 2026-10-02 | 2026-10-01 | ACOG Alpha Cognition Inc. | 10% | Buy | 19,050 | $165.6K | +0.4% | open → |
| 2026-10-01 | 2026-09-29 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 7,849 | $16.4K | -10.8% | open → |
| 2026-10-01 | 2026-09-23 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 5,318 | $11.2K | -11.2% | open → |
| 2026-10-01 | 2026-09-21 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 9,771 | $20.5K | -11.2% | open → |
| 2026-09-28 | 2026-09-25 | ACOG Alpha Cognition Inc. | 10% | Buy | 13,426 | $113.7K | +3.1% | open → |
| 2026-09-28 | 2026-09-24 | ACOG Alpha Cognition Inc. | 10% | Buy | 18,337 | $157.1K | +1.9% | open → |
| 2026-09-23 | 2026-09-23 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 5,318 | $11.2K | -11.2% | open → |
| 2026-09-23 | 2026-09-21 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 9,771 | $20.5K | -11.2% | open → |
| 2026-09-16 | 2026-09-16 | ACOG Alpha Cognition Inc. | 10% | Buy | 27,141 | $228.0K | +3.9% | open → |
| 2026-09-16 | 2026-09-16 | ACOG Alpha Cognition Inc. | 10% | Buy | 53,029 | $454.6K | +1.8% | open → |
| 2026-09-16 | 2026-09-15 | ACOG Alpha Cognition Inc. | 10% | Buy | 3,375 | $28.8K | +2.2% | open → |
| 2026-09-16 | 2026-09-14 | ACOG Alpha Cognition Inc. | 10% | Buy | 40,373 | $351.1K | +0.4% | open → |
| 2026-09-14 | 2026-09-11 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 1,493 | $98.5K | +3.6% | open → |
| 2026-09-14 | 2026-09-10 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 1,631 | $108.9K | +2.3% | open → |
| 2026-09-10 | 2026-09-09 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 5,836 | $12.2K | -10.8% | open → |
| 2026-09-10 | 2026-09-08 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 9,393 | $19.7K | -11.1% | open → |
| 2026-09-09 | 2026-09-09 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 3,097 | $212.8K | -0.6% | open → |
| 2026-09-09 | 2026-09-08 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 471 | $32.7K | -1.5% | open → |
| 2026-09-09 | 2026-09-08 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 3,390 | $233.0K | -0.6% | open → |
| 2026-09-09 | 2026-09-04 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 2,100 | $144.9K | -1.0% | open → |
| 2026-09-09 | 2026-09-04 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 918 | $63.8K | -1.8% | open → |
| 2026-09-03 | 2026-09-02 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 900 | $62.1K | -0.9% | open → |
| 2026-09-03 | 2026-09-01 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 783 | $54.4K | -1.8% | open → |
| 2026-08-31 | 2026-08-31 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 217 | $15.0K | -1.2% | open → |
| 2026-08-31 | 2026-08-31 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 5,000 | $341.2K | +0.1% | open → |
| 2026-08-31 | 2026-08-28 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 5,000 | $344.1K | -0.7% | open → |
| 2026-08-31 | 2026-08-28 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 20,113 | $1.38M | -0.2% | open → |
| 2026-08-31 | 2026-08-28 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 10,000 | $714.0K | -4.3% | open → |
| 2026-08-19 | 2026-08-14 | GRCE Grace Therapeutics, Inc. | 10% | Buy | 11,608 | $24.2K | -10.6% | open → |
| 2026-08-14 | 2026-08-12 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 951 | $68.0K | -4.5% | open → |
| 2026-08-04 | 2026-08-03 | ACOG Alpha Cognition Inc. | 10% | Buy | 50,000 | $400.0K | +9.1% | open → |
| 2026-08-04 | 2026-07-31 | ACOG Alpha Cognition Inc. | 10% | Buy | 2,900 | $23.0K | +10.2% | open → |
| 2026-07-28 | 2026-07-24 | ACOG Alpha Cognition Inc. | 10% | Buy | 130 | $1.0K | +10.5% | open → |
| 2026-07-24 | 2026-07-23 | ACOG Alpha Cognition Inc. | 10% | Buy | 49,849 | $388.6K | +12.0% | open → |
| 2026-07-24 | 2026-07-22 | ACOG Alpha Cognition Inc. | 10% | Buy | 10,000 | $78.3K | +11.4% | open → |
| 2026-07-24 | 2026-07-22 | ACOG Alpha Cognition Inc. | 10% | Buy | 140,237 | $1.10M | +11.4% | open → |
| 2026-07-17 | 2026-07-14 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 13,315 | $499.9K | +79.9% | open → |
| 2026-07-17 | 2026-07-14 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 15,000 | $563.1K | +79.9% | open → |
| 2026-07-16 | 2026-07-14 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 13,315 | $499.9K | +79.9% | open → |
| 2026-07-16 | 2026-07-14 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 15,000 | $563.1K | +79.9% | open → |
| 2026-07-15 | 2026-07-14 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 920 | $67.6K | -7.0% | open → |
| 2026-07-15 | 2026-07-13 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 775 | $57.3K | -7.6% | open → |
| 2026-07-10 | 2026-07-10 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 229 | $16.9K | -7.6% | open → |
| 2026-07-10 | 2026-07-08 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 300 | $22.1K | -7.3% | open → |
| 2026-07-07 | 2026-07-07 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 6,685 | $256.5K | +76.0% | open → |
| 2026-07-07 | 2026-07-07 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 20,000 | $767.5K | +76.0% | open → |
| 2026-07-07 | 2026-07-06 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 10,000 | $380.0K | +77.7% | open → |
| 2026-07-07 | 2026-07-02 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 25,000 | $934.6K | +80.7% | open → |
| 2026-07-07 | 2026-07-02 | ETON Eton Pharmaceuticals, Inc. | 10% | Sale | 65,000 | $2.43M | +80.7% | open → |
| 2026-06-29 | 2026-06-26 | ACOG Alpha Cognition Inc. | 10% | Buy | 152,336 | $975.2K | +36.4% | open → |
| 2026-06-29 | 2026-06-25 | ACOG Alpha Cognition Inc. | 10% | Buy | 197 | $1.3K | +34.3% | open → |
| 2026-06-16 | 2026-06-15 | ACOG Alpha Cognition Inc. | 10% | Buy | 4,550 | $27.3K | +45.8% | open → |
| 2026-06-16 | 2026-06-12 | ACOG Alpha Cognition Inc. | 10% | Buy | 273 | $1.6K | +47.2% | open → |
| 2026-06-16 | 2026-06-11 | ACOG Alpha Cognition Inc. | 10% | Buy | 2,862 | $16.9K | +47.8% | open → |
| 2026-06-11 | 2026-06-10 | ACOG Alpha Cognition Inc. | 10% | Buy | 5,872 | $35.2K | +45.8% | open → |
| 2026-06-11 | 2026-06-09 | ACOG Alpha Cognition Inc. | 10% | Buy | 24,856 | $148.5K | +46.1% | open → |
| 2026-06-09 | 2026-06-05 | ACOG Alpha Cognition Inc. | 10% | Buy | 10,054 | $58.6K | +49.8% | open → |
| 2026-05-29 | 2026-05-29 | ACOG Alpha Cognition Inc. | 10% | Buy | 70,577 | $416.4K | +48.0% | open → |
| 2026-05-29 | 2026-05-28 | ACOG Alpha Cognition Inc. | 10% | Buy | 2,000 | $11.7K | +49.7% | open → |
| 2026-05-29 | 2026-05-27 | ACOG Alpha Cognition Inc. | 10% | Buy | 1,161 | $6.7K | +52.4% | open → |
| 2026-05-22 | 2026-05-20 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 1,563 | $100.7K | +6.0% | open → |
| 2026-05-22 | 2026-05-21 | ACOG Alpha Cognition Inc. | 10% | Buy | 15,945 | $90.9K | +53.2% | open → |
| 2026-05-22 | 2026-05-20 | ACOG Alpha Cognition Inc. | 10% | Buy | 8,431 | $49.7K | +48.2% | open → |
| 2026-05-19 | 2026-05-18 | ACOG Alpha Cognition Inc. | 10% | Buy | 17,395 | $99.0K | +53.4% | open → |
| 2026-05-19 | 2026-05-15 | ACOG Alpha Cognition Inc. | 10% | Buy | 16,648 | $97.0K | +49.9% | open → |
| 2026-05-14 | 2026-05-13 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 1,937 | $129.5K | +2.1% | open → |
| 2026-05-14 | 2026-05-12 | SLGL Sol-Gel Technologies Ltd. | 10% | Buy | 1,500 | $102.0K | +0.5% | open → |
| 2026-04-21 | 2026-04-21 | SNWV SANUWAVE Health, Inc. | 10% | Sale | 202 | $4.1K | — | open → |
| 2026-04-21 | 2026-04-17 | SNWV SANUWAVE Health, Inc. | 10% | Sale | 5,000 | $102.3K | — | open → |
| 2026-04-21 | 2026-04-17 | SNWV SANUWAVE Health, Inc. | 10% | Sale | 11,267 | $230.5K | — | open → |
| 2025-01-02 | 2024-12-31 | CDXS CODEXIS, INC. | 10% | Buy | 10,000 | $46.6K | -78.5% | open → |
| 2025-01-02 | 2024-12-30 | CDXS CODEXIS, INC. | 10% | Buy | 35,000 | $164.5K | -78.7% | open → |
| 2025-01-24 | 2025-01-22 | HROW HARROW, INC. | 10% | Sale | 20,000 | $711.8K | -4.9% | open → |
| 2025-01-31 | 2025-01-30 | CDXS CODEXIS, INC. | 10% | Buy | 20,000 | $89.8K | -77.7% | open → |
| 2025-01-31 | 2025-01-31 | CDXS CODEXIS, INC. | 10% | Buy | 45,000 | $193.1K | -76.7% | open → |
| 2025-02-12 | 2025-02-11 | CDXS CODEXIS, INC. | 10% | Buy | 12,500 | $51.4K | -75.7% | open → |
| 2025-02-12 | 2025-02-12 | CDXS CODEXIS, INC. | 10% | Buy | 15,000 | $60.0K | -75.0% | open → |
| 2025-02-12 | 2025-02-10 | CDXS CODEXIS, INC. | 10% | Buy | 22,500 | $94.0K | -76.1% | open → |
| 2025-03-04 | 2025-03-03 | CDXS CODEXIS, INC. | 10% | Buy | 47,351 | $133.1K | -64.4% | open → |
| 2025-03-04 | 2025-02-28 | CDXS CODEXIS, INC. | 10% | Buy | 147,649 | $441.5K | -66.6% | open → |
| 2025-03-04 | 2025-02-28 | HROW HARROW, INC. | 10% | Sale | 5,000 | $140.3K | +20.6% | open → |
